Supporting Evidence-based Responses to Emotional Needs in Emphysema (SERENE): Protocol for a randomized, open-label mechanistic trial comparing Coping Skills Training and disease-specific education for depressive symptoms conducted in United States health systems TRIALS February 25, 2026 PAIR Center Research Team Joanna Hart Dan Carter Chloe Hinton Lily Brown Nora Brier Yingying Lu Casey Whitman Michael Harhay Carmen Alvarez